Protease inhibitor

Protease inhibitors (PIs) are a class of medications used to treat or prevent infection by viruses, including HIV and Hepatitis C. PIs prevent viral replication by inhibiting the activity of HIV-1 protease, an enzyme used by the viruses to cleave nascent proteins for final assembly of new virons. Protease inhibitors have been developed or are presently undergoing testing for treating various viruses: Given the specificity of the target of these d... more
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